Restylane injectable gel has been clinically proven to provide results that last up to 18 months, with only one follow-up treatment at either 4.5 or nine months. Your healthcare professional can work with you to help you establish your Restylane Regimen. Perlane injectable gel results may last up to six months after a single treatment.
Close

The Restylane Family of products instantly add volume to help restore youthful contours, so you’ll see results immediately following your treatment.
Close

Due to the individual needs of each patient, it is important to discuss your full correction with your healthcare professional. However, in a clinical study where patients received full correction for their nasolabial folds (lines from the nose to the corners of the mouth) during initial treatment in the Restylane Regimen, the average volume was 2 to 3 mL per patient.
Close

Products in the Restylane Family should not be used by people with previous bad allergies, particularly to certain microorganisms known as gram-positive bacteria, or by people with previous bad allergies to drugs who have required in-hospital treatment. These products should not be used by people with bleeding disorders. Injections should not be made anywhere except the skin or just under the skin. Restylane-L and Perlane-L should not be used by people with a known allergy to lidocaine. If you are pregnant, breastfeeding, or under 18 years, you should not use products in the Restylane Family.
Close

You should tell your healthcare professional if you have previously suffered from facial cold sores. He or she may prescribe a medication to minimize recurrence. You should also tell him or her if you have recently used aspirin, nonsteroidal anti-inflammatory medications, St. John’s wort, or high doses of vitamin E supplements. These agents may increase bruising and bleeding at the injection site.
Close

After your treatment, you may have some swelling, redness, pain, bruising, and tenderness. This will normally last less than seven days.
Close

How does Perlane work?

Just like Restylane, Perlane adds volume and fullness to the skin to correct moderate to severe facial wrinkles and folds, such as the lines from your nose to the corners of your mouth (nasolabial folds).

Like Restylane, Perlane is a clear gel formulation of hyaluronic acid that is specifically formulated to add fullness like your body’s own hyaluronic acid.

What makes Perlane different is the average size of the particles and the depth of injection. On average, the gel particles in Perlane are larger than those in Restylane, which makes Perlane a good choice for wrinkles that benefit from a deeper injection into the skin.

In three clinical studies of 150 patients each, on average 70% of patients maintained improvement for six months after just one Perlane treatment.

During your consultation, your healthcare professional will decide which product is right for you.

Get a more comfortable lift with Restylane-L and Perlane-L*

If you want a more youthful appearance, but you're concerned about the potential discomfort from treatment, you can get beautiful results and a more comfortable treatment experience with Restylane-L or Perlane-L.

By combining lidocaine with Restylane and Perlane, Restylane-L and Perlane-L help reduce discomfort during and after treatment.

In clinical studies evaluating the Restylane Family of products:

• 72% of patients reported significantly less pain during treatment with Restylane-L vs. Restylane.
• 95% of patients reported significantly less pain during treatment with Perlane-L vs. Perlane.
• Patients continued to experience less discomfort for up to one hour after treatment.

*When compared to Restylane and Perlane, respectively